Randomization Patients are to be randomized in the operation theatre, just after the skin harvest and hemostasis, and before the DSW is to be dressed. Itching scores are also collected by using a VAS, ranging from 0 (no itching) to 10 (intolerable itching) and obtained through the patient-held diary.
Wound infections, based on clinical symptoms of infection, scarring at 12 weeks postoperatively (using Patient and Observer Scar Assessment Scale (POSAS) assessed by the patients themselves and researchers, treating physicians or specialized wound nurses), patient satisfaction (varying from 1 (absolutely dissatisfied) to 10 (absolutely satisfied), and costs (material and nursing costs).
Secondary endpoints As secondary endpoints we assess the occurrence of local complications, e.g. Both primary endpoints are meaningful and relevant to patients and were therefore used for the sample size calculation.
